The size-wise nucleus: nuclear volume control in eukaryotes
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The size-wise nucleus: nuclear volume control in eukaryotes
Eukaryotic cells have an "awareness" of their volume and organellar volumes, and maintain a nuclear size that is proportional to the total cell size. New studies in budding and fission yeast have examined the relationship between cell and nuclear volumes. It was found that the size of the nucleus remains proportional to cell size in a wide range of genetic backgrounds and growth conditions that...
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The nucleus is one of the most prominent cellular organelles, yet surprisingly little is known about how it is formed, what determines its shape and what defines its size. As the nuclear envelope (NE) disassembles in each and every cell cycle in metazoans, the process of rebuilding the nucleus is crucial for proper development and cell proliferation. In this Commentary, we summarize what is kno...
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Diversity is one of the most significant features of life. The current assessment of biodiversity on Earth reaches several millions of living species, and an unimaginable number of species that have gone extinct. Further more, diversity is ingrained in all aspects of life, namely, genetics, metabolic needs, cell complexity, body plans and organismal morphology , developmental programs, behavior...
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ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 2007
ISSN: 1540-8140,0021-9525
DOI: 10.1083/jcb.200710156